The Heart/Thorax Phantom is ideal for evaluation of detectability, extent and severity of myocardial infarcts in patients. This Phantom also provides valid assessment of mammoscintigraphy techniques.The Striatal Phantom optimizes quantitative imaging in patients, using PET or SPECT.
Myocardial perfusion SPECT is a widely-used, non-invasive method for the diagnosis and management of patients with coronary disease. However, non-uniform photon attenuation, Compton scatter, limited and depth-dependent spatial resolution, as well as image noise, limit the ability of SPECT to obtain images that reliably represent the true tracer distribution. The non-uniform attenuation of the thorax is the most significant factor limiting the diagnostic efficacy of myocardial SPECT.
The currently used attenuation, scatter and resolution correction methods are suboptimal, since they do not provide improvement in the 25% false-negative findings in a group of about 100 patients with luminal diameter stenoses of at least 50%. Furthermore, the ability to detect multivessel disease was 70% without and 47% with corrections. This finding implies that myocardial SPECT can seriously underestimate the extent of disease in high-risk patients. On the other hand, the false-positive findings in the group with a low probability of coronary disease were reduced from 14% without corrections to 3% with corrections.
Obviously, further improvements in both hardware and software for myocardial SPECT are necessary before this important diagnostic technique can realize its full potential. These improvements must be carefully evaluated on realistic, anthropomorphic phantoms to improve results in clinical practice.